Aegirin syenite from Iwaki I., Ehimi Pref.

Pref-1, a Gatekeeper of Adipogenesis

Preadipocyte factor 1 (Pref-1, also called Dlk1/FA1) is a molecular gatekeeper of adipogenesis which acts by maintaining the preadipocyte state and preventing adipocyte differentiation. Pref-1 is made as an epidermal growth factor-like repeat containing transmembrane protein, and is cleaved by TNFα-converting enzyme (TACE) to generate a soluble form, which acts as an autocrine/paracrine factor....

Carbon, cesium and iodine isotopes in Japanese cedar leaves from Iwaki, Fukushima

Japanese cedar leaves from Iwaki, Fukushima were analyzed for carbon, cesium and iodine isotopic compositions before and after the 2011 nuclear accident. The Δ14C values reflect ambient atmospheric 14C concentrations during the year the leaves were sampled/defoliated, and also previous year(s). The elevated 129I and 134,137Cs concentrations are attributed to direct exposure to the radioactive f...

I-19: From

Feldspar and Nepheline Syenite Potential in British Columbia

Feldspathic materials are used in the glass and ceramic industries as a source of alkalis, alumina and silica. These elements affect the rate and temperature of melting. fluidity of the melt and physical properties of the finished product. Silica, sodium, potassium and alumina ratios in the feldspar product vary for each industrial user, however, iron must be limited to less than 0. I per cent ...

Pref-1 preferentially inhibits heat production in brown adipose tissue.

In mammals there are two types of adipocytes with opposing functions. Brown adipocytes are characterized by a high number of mitochondria and are specialized for heat production (thermogenesis), expressing thermogenic genes such as UCP1 (uncoupling protein 1). White adipocytes, on the other hand, store energy. Although many key regulators in the differentiation of white adipocytes have been est...